Comparison: Best Drain Cleaner For Grease (Updated | Oct 22nd)

Clogged drains caused by grease buildup can be a persistent nuisance in households and commercial settings. Finding the right drain cleaner is essential for maintaining smooth plumbing while avoiding damage to pipes. This comparison explores top options designed to tackle grease effectively, evaluating factors like potency, safety, and environmental impact. Whether you prefer chemical solutions, enzymatic formulas, or mechanical methods, the goal is to help you identify a reliable, practical choice for keeping your drains clear without compromising long-term pipe health.

Product Comparison: Best Drain Cleaner For Grease

Best overall

Green Gobbler Enzyme Drain Cleaner | Controls Foul Odors & Breaks Down Grease, Paper, Fat & Oil in Sewer Lines, Septic Tanks & Grease Traps | 1 Gallon

Green Gobbler Enzyme Drain Cleaner | Controls Foul Odors & Breaks Down Grease, Paper, Fat & Oil in Sewer Lines, Septic Tanks & Grease Traps | 1 Gallon

Green Gobbler
  • ENZYME ENHANCED FORMULA: Green Gobbler Enzymatic Drain & Grease Trap Cleaner uses an enzyme enhanced formula to clear buildup and remove odors in grease traps, septic tanks and similar plumbing systems. It helps digests oils, fats, grease, sludge and other food waste within hours of application. This bottle uses anti-glug technology to help reduce splashing and provides up to eight treatments.
  • SAFE FOR PIPES: Green Gobbler helps maintain drain lines, septic tanks, grease traps and grease interceptors. Our enzyme enhanced formula is an excellent alternative to sodium hydroxide and other caustic chemicals.
  • IMPROVE GREASE TRAP EFFICIENCY: Green Gobbler increases the efficacy of grease traps by allowing enzymes & bacteria to work more efficiently to promote the separation of water and grease, helping your trap run more smoothly.
  • KEEP SEPTIC TANKS HEALTHY: Green Gobbler helps prompt the biological breakdown of foul odors and organic material inside demanding environments such as drains, pipes and septic tanks.
  • GREEN GOBBLER GUARANTEE: Green Gobbler cares about its customers. We take pride in developing innovative & effective products for your home or business. If for any reason you are unsatisfied, please contact us. We offer a money-back guarantee within 30 days of purchase.

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Fastest action

Drano Max Gel Drain Clog Remover and Cleaner for Shower or Sink Drains, Unclogs and Removes Hair, Soap Scum and Blockages, 80 Oz, Pack of 2

Drano Max Gel Drain Clog Remover and Cleaner for Shower or Sink Drains, Unclogs and Removes Hair, Soap Scum and Blockages, 80 Oz, Pack of 2

Drano
  • TRUSTED BRAND: Drano Max Gel Drain Clog Remover is the #1 Selling Gel Drain Cleaner*. Avoid spending money on a plumber and use Drano.
  • FAST-ACTING: Starts working in 7 minutes. For best results, pour 16 oz slowly over drain. For extremely slow-running drains or complete clogs, use 32 oz. Allow Drano to sit for 15-30 minutes and flush with hot tap water. Repeat if necessary.
  • REMOVES CLOGS: Pours through standing water straight to the clog. Use Drano whenever major clogs occur.
  • SAFE ON PIPES: Safe for bathroom and kitchen sinks. Drano Max Gel includes an ingredient to protect pipes from corrosion over time without compromising the efficacy of the clog remover.
  • GREAT FOR PREVENTING CLOGS: Act on slow running drains before the clog forms. Cheaper than a plumber.

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Powerful gel

Instant Power Hair and Grease Drain Cleaner – Shower Drain & Sink Cleaner, Liquid Clog Remover, Made in USA, Sink Deodorizer – 1 Liter (Pack of 2)

Instant Power Hair and Grease Drain Cleaner - Shower Drain & Sink Cleaner, Liquid Clog Remover, Made in USA, Sink Deodorizer - 1 Liter (Pack of 2)

Instant Power
  • POWERFUL FORMULA THAT WORKS FAST – A powerful sink de-clogger that works in minutes and is safe for all sinks, tubs, showers, RV drains, and septic systems – 20x stronger than common drain openers
  • LIQUEFIES ORGANIC MATERIALS – Effectively dissolves hair and creates heat to melt grease without using ingredients that can damage your drain. All while being odorless and without producing fumes
  • HELPS ELIMINATE ODORS – Bad odors inside or outside your home could indicate that your drains are backed up; Instant Power Hair and Grease Cleaner helps reduce odor as it unblocks your drains
  • EASY TO USE AT HOME – Just pour into your drain and let it work – no tools or complicated steps required. A simple way to tackle buildup in sinks, tubs, and showers
  • SERIOUS CLOG-BUSTING POWER – Instant Power's line of drain cleaners, hair removers, and septic system products is made to deliver reliable results and help keep your home or business flowing smoothly

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Best budget

Amazon Basics Max Strength Drain Cleaner Hair Clog Remover Gel – Unclogs Hair and Grease, 80 Fl Oz

Amazon Basics Max Strength Drain Cleaner Hair Clog Remover Gel - Unclogs Hair and Grease, 80 Fl Oz

Amazon Basics
  • Safety Seal added to help prevent leakage during shipping.
  • MAX STRENGTH FORMULA: Lab-tested gel combines powerful ingredients in our drain clog remover liquid to dissolve hair, grease, and gunk. Best results if product is at room temperature and flushed with very hot water
  • SAFE ON ALL PIPES: Phosphate-free bathroom sink drain cleaner provides safe use on all pipes, garbage disposals, and septic systems without corrosion or damage. Not intended for us on clogged toilets
  • QUICK ACTION: Starts working on contact, cutting through water blockages to effectively open blockages with our drain opener, perfect for clearing slow-flowing drains fast
  • EASY-POUR DESIGN: The drain cleaner's "No-Glug" bottle reduces splashing, with an ergonomic handle built for effortless and precise application
  • MULTI-USE CAPABILITY: Ideal for kitchen, bathroom, shower, and tub drains. This septic safe drain clog remover is perfect for monthly maintenance to prevent future clogs
  • TRY IT: If you like Drano Max Gel Drain Clog Remover, we invite you to try Amazon Basics Max Strength Gel Drain Clog Remover

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Tough clogs

Green Gobbler Industrial Strength Grease and Hair Drain Clog Remover | Drain Cleaner Gel | Safe for Pipes, Toilets, Sinks, Tubs, Drains & Septic Systems | 1 Gallon

Green Gobbler Industrial Strength Grease and Hair Drain Clog Remover | Drain Cleaner Gel | Safe for Pipes, Toilets, Sinks, Tubs, Drains & Septic Systems | 1 Gallon

Green Gobbler
  • ELIMINATE THE TOUGHEST CLOGS: Liquefy hair, grease, toilet paper, soap scum, organic material, flushable wipes and more. This bottle uses anti-glug technology to help reduce splashing and provides up to eight clog remover treatments.
  • EASY TO USE: Forget the plumber. Pour Green Gobbler in standing water and it will do the rest. The Industrial Strength gel is our thickest formula to cling to clogs better and keep your pipes flowing properly.
  • WORKS ON: Toilets, sinks, showers, tubs, and drains. It's safe for all pipes and septic tanks.
  • BLEACH FREE FORMULA: Odorless and free of fumes, Green Gobbler Industrial Strength is an excellent alternative to traditional bleach-based drain openers.
  • GREEN GOBBLER GUARANTEE: Green Gobbler cares about its customers. We take pride in developing innovative & effective products for your home or business. If for any reason you are unsatisfied, please contact us. We offer a money-back guarantee within 30 days of purchase.

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Odor eliminator

Adios! Professional Grease Trap Cleaner for FOG – Cleans Fats, Oils & Grease from Drains Pipes, Safe Enzyme Based Formula for Preventative Maintenance

Adios! Professional Grease Trap Cleaner for FOG – Cleans Fats, Oils & Grease from Drains Pipes, Safe Enzyme Based Formula for Preventative Maintenance

ADIOS!
  • FAST ENZYME FORMULA – Say goodbye to harsh and dangerous chemicals with Adios! Professional Grease Trap Cleaner. Our powerful enzyme formula quickly works to eliminate organic material trapped in pipes. Restore your sink drains safely and naturally!
  • CUTS THROUGH FOG – Breaks down and removes fats, oils, grease, waste and organic material that clog and slow down drains. Potent formula works on the cellular level to clear out even the most difficult grease traps.
  • CLOG WARNING – Adios! Grease Trap Cleaner is a preventative maintenance product to prevent clogs from happening. It is not a drain opener or used to unclog grease traps that have not been maintained.
  • ELIMINATES FOUL ODORS – Say goodbye to stinky sinks and pipes! Adios Drain Cleaner removes bad smells at the source, flushing out the system and bringing peace of mind to your kitchen and staff.
  • SAFE FOR STAFF – Our enzyme cleaner is 100% safe to handle and contains no harsh chemicals. Traditional commercial grease trap cleaners use lye, a highly dangerous substance that requires training.

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Eco-friendly solution

Bio-Clean Drain Septic 2# Can Cleans Drains- Septic Tanks – Grease Traps All Natural and 100% Guaranteed No Caustic Chemicals! Removes fats Oil and Grease, Completely Cleans Your System.

Bio-Clean Drain Septic 2# Can Cleans Drains- Septic Tanks - Grease Traps All Natural and 100% Guaranteed No Caustic Chemicals! Removes fats Oil and Grease, Completely Cleans Your System.

Bio-Clean
  • LISTING IS FOR 1 TWO POUND CANISTER
  • Special combination of natural microbes and enzymes that DIGESTS dead organic waste found in your plumbing system
  • Eliminates costly backups. Up to 100 Drain Treatments.
  • Environmentally friendly and safe.
  • Multi Purpose. Kitchen sinks, showers, bath tubs, garbage disposals, septic tanks & fields, cat litter pans, motor homes and much more!

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Pipe protector

Liquid-Plumr Pro-Strength Clog Destroyer, Liquid Drain Cleaner, 80 Fluid Ounces (Package May Vary)

Liquid-Plumr Pro-Strength Clog Destroyer, Liquid Drain Cleaner, 80 Fluid Ounces (Package May Vary)

Clorox
  • DRAIN CLOG REMOVER: This Liquid-Plumr Pro-Strength Clog Destroyer Gel is fortified with 3X action to protect, prevent and destroy clogs; Packaging may vary
  • WORKS ON MULTIPLE CLOG TYPES: This gel clog remover tackles the toughest clogs from hair (2), grease and soap scum and cuts through standing water to clear total blockages
  • SAFE ON ALL PIPES: Made with Pipeguard, this Liquid-Plumr drain cleaner protects pipes and is safe for septic systems, disposals (3) and pipes, including PVC, plastic, copper and old drain pipes
  • ODOR ELIMINATOR: Pro-Strength Clog Destroyer works great on bathtubs, bathroom sinks, showers, kitchen sinks and garbage disposals (3); Do not use with plunger or in toilets
  • MAINTAIN CLEAR PIPES AND DRAINS: When used monthly, this Liquid-Plumr Pro-Strength Clog Destroyer prevents clogs from coming back (1) in your pipes or drains

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Septic safe

Bioda Professional Strength Enzyme Drain Cleaner, Septic Safe Drain Odor Eliminator, Smell Eliminator

Bioda Professional Strength Enzyme Drain Cleaner, Septic Safe Drain Odor Eliminator, Smell Eliminator

Bioda
  • END SLOW DRAINS: Stop clogs from ever building with a preventative probiotic and enzyme formula that digest organic waste in your plumbing system
  • KEEPS DRAINS FLOWING: Our unique blend of enzymes and probiotics break down the buildups from grease, soap scum, and food particles
  • PIPE AND SEPTIC SAFE: Our septic safe drain cleaner uses beneficial bacteria to break down clogs rather than harsh chemicals that can damage your pipes and septic systems
  • ELIMINATES ODORS: Our drain odor eliminator breaks down the odors at the source. Removing the grease, fats and other organic matter that cause the smell
  • MULTIPURPOSE CLEANER: Our drain cleaner can be used wherever needed – your Kitchen Sink, Bathroom Sink, Garbage Disposal, Sewers, Bathtub Drains, Shower Drains, Boat Holding Tanks and RV Holding Tanks

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Bacteria enhanced

Roebic K-97 Liquid Main Line Cleaner with Bacteria Enzymes, Eliminates Organic Buildup in Sewer/Septic System and Protects from Clogs, Safe for Bathroom Toilet, 32 fl oz

Roebic K-97 Liquid Main Line Cleaner with Bacteria Enzymes, Eliminates Organic Buildup in Sewer/Septic System and Protects from Clogs, Safe for Bathroom Toilet, 32 fl oz

Roebic
  • Roebic, 32oz main line sewer/septic cleaner, concentrated bacterial waste degrading product for any sewer line, clears fats, grease, sludge, & paper, for any household use, whether septic system or sewer.
  • Safe for all pipes and the environment.
  • Naturally breaks down waste accumulated and quickly restores proper flow.
  • Keeping your lines problem free.

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Product prices and availability are accurate as of the date/time indicated and are subject to change. Any price and availability information displayed on Amazon.com at the time of purchase will apply to the purchase of this product.

Buying Guide

Buying Guide: Best drain cleaner for grease

Formulation Type

  • Choose between enzymatic, gel, or chemical-based cleaners
  • Enzymatic options are eco-friendly and safe for pipes
  • Gel-based formulas cling to clogs for targeted action

Effectiveness on Grease

  • Look for products that break down fats, oils, and grease (FOG)
  • Check if the formula digests grease or dissolves it chemically
  • Prioritize cleaners tested for heavy grease buildup

Safety & Compatibility

  • Ensure compatibility with your plumbing material (PVC, metal, etc.)
  • Verify if the product is safe for septic systems
  • Avoid caustic chemicals if concerned about pipe corrosion

Application & Ease of Use

  • Opt for anti-glug or easy-pour designs to minimize mess
  • Check if the product works in standing water
  • Consider pre-measured packets or dosing instructions for convenience

Odor Control

  • Select formulas that neutralize foul smells at the source
  • Enzyme-based cleaners often eliminate odors during grease breakdown
  • Avoid bleach-based options if sensitive to strong fumes

Preventive vs. Immediate Action

  • Use enzymatic cleaners regularly to prevent grease buildup
  • Gel-based cleaners are better for sudden, severe clogs
  • Check if the product is labeled for maintenance or emergency use

FAQs

Which drain cleaner is best for dissolving grease?

Green Gobbler Enzyme Drain Cleaner breaks down grease effectively.

Are there septic-safe grease cleaners?

Bio-Clean Drain Septic Cleaner and Bioda Professional Strength Enzyme Drain Cleaner are septic-safe.

Which option is strongest for heavy grease buildup?

Green Gobbler Industrial Strength Grease and Hair Drain Clog Remover is designed for tough grease.

What works for grease traps in commercial settings?

Adios! Professional Grease Trap Cleaner targets fats, oils, and grease in traps.

Which gel-based cleaner handles grease well?

Amazon Basics Max Strength Drain Cleaner Gel removes grease clogs effectively.

Are there enzyme-based options for grease?

Roebic K-97 Liquid Main Line Cleaner uses bacteria and enzymes to eliminate grease.

What drain cleaner is fast-acting for grease?

Instant Power Hair and Grease Drain Cleaner provides quick grease removal.

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